The 3D spheroid system is functionally stable and suitable for chronic applications, thus allowing to assess long-term toxicity and induction not supported by conventional in vitro systems due to the rapid loss of hepatic phenotypes and functions.

The use of human cells instead of animal models allows direct translation of findings to patients.

The spheroid system is optimized to support co-cultures with non-parenchymal cells, such as Kupffer, biliary and Stellate cells, to more closely resemble the cellular repertoire of the liver, which allows studies of inflammatory processes reliant on hepatocyte - immune cell interactions and permits to capture complex DILI events.

As the 3D spheroids capture the phenotypic variability between individuals in vitro, employing cells from multiple donors simulates small “clinical trials”, thus considerably reducing costs and time for the customer.

Scalability of the system in 96-well format allows screening of dozens of conditions and/or drug candidates with multiple replicates in a single experiment.

Controlled experimental conditions, such as precisely defined spheroid sizes and chemically-defined, serum-free culture conditions ensure maximal reproducibility. Moreover this setting facilitates mechanistic insights, which can aid in targeted compound optimizations to circumvent toxicity.

As part of our business philosophy we offer extensive customer support from project initiation to closure. Before project launch, we discuss customer expectations and tailor the experimental designs and readouts to the particular needs.

We perform an integrative analysis in which the results are interpreted by certified experienced toxicologists.

The final report is delivered to the customer and contains the experimental results, their toxicological interpretation as well as consulting about future steps and recommendations for follow-up studies, thus facilitating rapid progress of the project in question.

As projects are highly individualized, the duration of the experimental phase depends on assay, endpoints of interest, number of donors etc. The time from finalization of experimental results to interpretation and delivery typically takes 1-2 weeks.

Shipping

In case physical items require transportation, we ship out within two days of purchase. We determine the most efficient shipping carrier for your order. The carriers that may be used are: DHL, United Parcel Service (UPS) or FedEX. If you're trying to estimate when a package will be delivered, please note the following:

Credit card authorization and verification must be received prior to processing. DHL, FedEX and UPS deliveries occur Monday through Friday, excluding holidays. If you require express or 2 day shipping, please contact us for charges.

Returns

All refunds will be provided as a credit to the credit card used at the time of purchase within five (5) business days upon receipt of the returned merchandise.

HepaPredict AB takes the privacy of those that visit our web site very seriously. We have established this Privacy Policy to communicate what information we collect and how that information is used and safeguarded.

By accessing this website, you acknowledge the terms and conditions expressed herein. We reserve the right to change this policy at our sole discretion and without notice.

What information is collected, and why?

When a user visits our website, we collect information about the visit that does not identify the user personally. We track information such as the domain from which the user is visiting and the user's browser type. We also collect specific information regarding the user's session on our website. This includes items such as the date and time of the visit and the pages viewed.

We might ask a user to voluntarily provide personally identifiable information (PII). This information generally includes, but is not limited to, name, e-mail address, postal address, and telephone number. We request this information when the user requests one of the following:

• To register to attend a seminar or demonstration

• To receive specific information from us such as a certain scientific data or samples

• To sign up for a mailing list

• To correspond with us

• Or any other such activity that we deem necessary

HepaPredict AB does not collect any personally identifiable financial or health-related information. We do not intentionally collect information from minors.

How is the information used?

Non-personally identifiable information (non-PII) is collected to allow us to analyze how our website is used and to improve the content and service the website provides.

Personally identifiable information is collected for analysis to improve the content of the website and the services we provide the user.

HepaPredict AB owns the collected information and will not sell, trade, or rent the information to others. We may use the information to continue contact with the user. This may include contact such as follow-up calls, e-mail correspondence, or mail correspondence to follow-up on the contact or to provide marketing information about promotions, new services, or important website changes. HepaPredict AB may share this information with its business partners for the specific purpose of a promotion or service offering.

Are "Cookies" used on the website?

We may use cookies to provide you with better service.

Cookies are pieces of information that a Web site transfers to your computer's hard disk for record-keeping purposes. Cookies can make the Web more useful by storing information about your preferences for a particular site and many major Web sites use them to provide useful features for their customers. Cookies in and of themselves do not personally identify users, although they do identify a user's computer. The use of cookies is an industry standard and most browsers are initially set to accept cookies. If you prefer, you can set your browser to refuse cookies. However, you may not be able to take full advantage of the functionality of HepaPredict AB's site if cookies are disabled.

How is personally identifiable information safeguarded?

HepaPredict AB utilizes industry standard methods and mechanisms such as firewalls, intrusion monitoring, and passwords to protect electronic information. Access to PII is limited to a small number of personnel and on a need-to-know basis.

Links to other web sites

The HepaPredict AB web site may contain links to other internet web sites. HepaPredict AB neither controls external sites nor are we responsible for the content of such sites.

How to opt out of correspondence

Based on the information a user has provided, HepaPredict AB may send e-mail correspondence to the user. Upon request, the addressee can opt out of further correspondence.

HepaPredict AB data protection policy

HepaPredict AB handles personal data only for specific purposes e.g. to handle data relevant for the work we do with regards to projects conducted at HepaPredict AB.

Approval of handling of personal data

By contacting HepaPredict AB for support the applicant confirms the approval of handling of his/her general personal data.

Why is my personal data collected and handled?

Personal data is only collected and handled by HepaPredict AB for specific purposes e.g. to be able to contact, inform and follow up on any projects or collaborations done between the customer and HepaPredict AB. The personal data is collected and handled for the administration of contacts, communication, and relevant reports.

For how long will my personal data be kept?

Personal data is kept only for as long as it is needed to fulfill the purposes for which it was collected. When a collaboration has ended, personal data is removed on a regular basis. Some data must be kept for a longer period for accounting purposes.

Who will have access to my personal data?

Only authorized HepaPredict staff has access to the personal data. The personal data is registered in a system that is protected from infringement. Your right as a collaborator with HepaPredict AB You have the right to ask for a transcript of the data that HepaPredict AB has registered about you, once per year, free of charge. The transcript request should be signed in handwriting and be sent by regular mail to HepaPredict AB, Nobels väg 16, SE-171 77 Stockholm, Sweden.

GDPR at HepaPredict AB

A new data protection regulation, GDPR (General Data Protection Regulation) for the processing of personal data will be applied on May 25, 2018, in Sweden. At this link you can find information on the Data Protection Regulations (EU) 2016/679 of the European Parliament.